Fig. 5
From: Serine synthesis and catabolism in starved lung cancer and primary bronchial epithelial cells
Lower glycolytic intermediates in high or low serine/glycine or glucose. Total abundance (normalized to protein and internal standard) of phosphoenolpyruvate (PEP) and pyruvate from experiments shown in Fig. 3. Results are mean ± SEM from four (A549 and H1299) or three (BEC) experiments. Group comparisons were performed by Two-way ANOVA with Tukey post-hoc analysis; *P < 0.05; **P < 0.01; ***P < 0.001; n.s., not significant; # versus high glucose conditions. Ser/Gly, serine/glycine; Right: Known allosteric modulators of lower glycolysis. PK, pyruvate kinase; PDH, pyruvate dehydrogenase