Fig. 2

Increased RPS27 expressed in prostate cancer in HFD mice. A The dataset GSE90912 was analyzed to identify differentially expressed genes in prostate tumors in CD and HFD mice; Dataset we used here is part of GSE90905 (a subseries of superseries GSE90912) including GSM2417319, GSM2417320, GSM2417321, GSM2417325, GSM2417326, GSM2417327. This dataset is an expression profiling by RNA-Seq for PCa model mice fed CD or HFD [6]. B, C Survival map of up-regulated genes in PCa (B) and Kaplan–Meier analysis of the correlation between RPS27 expression and disease-free survival in prostate adenocarcinoma patients (C) via GEPIA2; Group cutoff: quartile; Datasets selection: PRAD; D mRNA expression level and E protein level of RPS27 in splenic orthotopic tumors; *P < 0.05; **P < 0.01; ***P < 0.001