Fig. 3

The restricted cubic spline curves of CTI in the different cohorts of patients with cancer cachexia. A, B Total cohort, A Unadjusted, B Adjusted for model 4; C, D Internal test cohort, C Unadjusted, D Adjusted for model 4; E, F External validation cohort, E Unadjusted, F Adjusted for model 4; Model 4: adjusted for age, sex, BMI, tumor stage, tumor type, KPS, surgery, chemotherapy, radiotherapy, smoking status, alcohol consumption, KPS, EORTC QLQ-C30, ECOG PS, PGSGA, diabetes, hypertension, coronary heart disease, and TSF. Notes: CTI, C-reactive protein-triglyceride glucose index; BMI: body mass index; KPS, karnofsky performance status; EORTC QLQ-C30, The European Organization for Research and Treatment of Cancer (EORTC), Quality of Life Questionnaire-Core 30 (QLQ-C30); ECOG PS: eastern cooperative oncology group performance status; PGSGA, Patient Generated Subjective Global Assessment; TSF, triceps skinfold thickness