Fig. 7From: Deficiency of TOP1MT enhances glycolysis through the stimulation of PDK4 expression in gastric cancerPDK4 was required for the upregulation of migration and lactate production in GC cells induced by TOP1MT silencing. A Western blot analysis for the detection of PDK4 expression in MGC-803 and HGC-27 cells. B The effects of M77976 on TOP1MT expression were analyzed by western blot. C Cell migration was assessed by transwell migration assays. D Representative experiments showing pH determination (BCECF-AM) after 48 h of culture in different groups. P values * < 0.05 and ** < 0.01Back to article page