Fig. 2From: ATM inhibition blocks glucose metabolism and amplifies the sensitivity of resistant lung cancer cell lines to oncogene driver inhibitorsLevels of extracellular glucose and intracellular metabolic intermediates in response to ATM inhibition. A Levels of residual glucose in culture media of H1993 and H1975 cells exposed to 10-nM and 100-nM of KU55933 for 48 h. Levels of intracellular B pyruvate, C citrate, and D succinate in H1993 and H1975 cells exposed to 100-nM of KU55933 for 48 h. Symbol * indicates a p-value < 0.05, symbol ** indicates a p-value < 0.01, symbol *** indicates a p-value < 0.001 versus NTBack to article page