Fig. 2From: Restoring gluconeogenesis by TEF inhibited proliferation and promoted apoptosis and immune surveillance in kidney renal clear cell carcinomaPromoting gluconeogenesis inhibited the proliferation, clone formation, and induced apoptosis in renal carcinoma cells. A The relative expression of indicated genes in tumor and adjacent tissues was tested by QPCR. N = 10. B The relative expression of indicated genes in kidney tumor and normal cell lines was tested by QPCR. N = 5. C The levels of cellular glucose (left) and lactate (right) in Caki-1 and 769-P cells. N = 3. C Colony formation assay comparing Caki-1 and 769-P transfected with PCK1 overexpression lentivirus control vector. D After transfected with PCK1 OE or control vector, the cell viability of Caki-1 and 769-P cells was tested at indicated time points by CCK8 assay. E The level of apoptosis of Caki-1 and 769-P cells transfected with PCK1 OE or control vector was analyzed by Annexin V and PI staining by flow cytometry. *P < 0.05Back to article page